In a move that is sure to set the music world alight, Lady Gaga has been announced as the headliner for Coachella 2025, a triumphant return that will be one of the most anticipated performances of the year. The iconic artist, who has always been known for pushing the boundaries of pop music and live performance, will debut her latest single’s electrifying new version, “DISEASE (THE POISON LIVE),” during the festival. This rendition of her lead single from the forthcoming album, expected in February 2025, adds yet another layer to her evolving sonic exploration, capturing the raw energy of her artistry.
Lady Gaga – DISEASE (THE POISON LIVE) – Marcell Rév
Lady Gaga, a 13-time Grammy Award winner, has always been a master of reinvention, and her new material is no exception. “DISEASE (THE POISON LIVE),” released today, is a guitar-driven reinterpretation of the original track, showcasing the artist’s versatility and intimate musicianship. Produced by Lady Gaga herself, the new version follows last week’s acoustic release, “DISEASE (THE ANTIDOTE LIVE),” demonstrating her ability to transform powerful pop anthems into nuanced, multidimensional experiences. Where “The Antidote” highlighted Gaga’s delicate and emotional side, “The Poison” is a force of nature—a visceral, stripped-down take that allows her voice and a commanding guitar arrangement to take center stage.
“DISEASE” was first released on October 25, and from the moment it dropped, critics and fans alike have been captivated by the song’s emotional resonance and bold production. Each version of the track has shed light on different elements of Gaga’s songwriting prowess, with “The Antidote” offering a more vulnerable angle, and “The Poison” turning up the intensity in a thrilling way. Harper’s Bazaar described the original track as “classic Gaga in the best way,” while BBC lauded its “dark, dazzlingly maximalist” sound. The Independent called it “her best in a long while,” with its “potent dose of dungeon-dark electro-pop” providing a thrilling return to Gaga’s roots. The praise has only deepened with each new iteration, as audiences are treated to the versatility that has become a hallmark of Gaga’s ever-evolving sound.
Lady Gaga – DISEASE – Jasmine Safaeian
The accompanying music video, directed by Tanu Muino, adds another layer of depth to the track. The cinematic visuals have received rave reviews, with Vogue declaring it “one of the best videos of the year.” Muino’s direction, described as “a cinematic, almost theater-like experience” by W magazine, underscores the haunting and passionate themes of the song, drawing viewers into Gaga’s vivid, sometimes unsettling, artistic world. The video’s theatricality and dark allure perfectly align with the track’s sonic themes, creating a holistic and immersive experience that has become a hallmark of Lady Gaga’s creative vision.
Lady Gaga’s performance at Coachella will no doubt be a defining moment for the festival, as she brings her latest chapter to one of the world’s most iconic stages. Her past performances have set the bar high—whether it’s the extravagance of her Super Bowl Halftime Show, the glamorous spectacle of her Las Vegas residency, or her previous Coachella appearance in 2017. For Coachella 2025, Gaga has promised to deliver something entirely new, a showcase of her latest material that blends genre-defying sounds, stunning visuals, and her unmistakable stage presence. It’s clear that this will be a moment of transformation for Gaga, one that highlights her as an artist continuously evolving and redefining the boundaries of pop music.
“DISEASE” is more than just a song; it’s a glimpse into what Gaga has in store for her forthcoming album, affectionately dubbed LG7. Rooted in pop, yet unafraid to explore other genres and textures, LG7 promises to be an expansive, deeply personal work that traverses themes of vulnerability, intensity, and soulful expression. With “DISEASE (THE POISON LIVE)” and “DISEASE (THE ANTIDOTE LIVE),” Lady Gaga has given us a taste of this dynamic new era, one that feels both nostalgic and refreshingly innovative. Her willingness to push the sonic boundaries, whether by embracing guitar-driven arrangements or stripping everything back to a bare emotional core, reminds us why she remains one of the most compelling artists of her generation.
Lady Gaga’s headline performance at Coachella will be one to watch—not just for the spectacle, but for the emotional resonance of her music, which has always been at the heart of her artistry. With the debut of “DISEASE (THE POISON LIVE),” Coachella 2025 will serve as the perfect platform for Lady Gaga to usher in her next chapter, delivering a performance that will undoubtedly be remembered for years to come. As the world eagerly awaits the release of her next album, Gaga is proving once again that she is capable of creating not just songs, but sonic experiences that linger long after the final note has played.
